| 1982 |
Hashima Laboratory, Nihon Bioresearch Inc. (NBR) established by investments from Kitayama Labes Co., Ltd. and Oriental Yeast Co., Ltd. |
| Commenced GLP-compliant safety studies. |
| 1985 |
First audit for GLP compliance for drugs (latest audit: 2015). |
| 1986 |
Commenced pharmacological studies. |
| 1988 |
First audit for GLP compliances for pesticides. |
| 1994 |
First audit for GLP compliances for Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Japanese Ministry of Health and Welfare) (latest audit: 2015) and for feed additive. |
| 1995 |
Commenced manufacturing agar plate medium for Ames tests. |
| 1999 |
Commenced operation of our own developed computer system for nonclinical studies. |
| 2002 |
Shuzenji Branch specialized for minipigs established, and commenced pharmacological and safety studies. |
| 2004 |
First audit of Shuzenji Branch for GLP compliance for drugs. |
| 2005 |
A Part 11-compliant computer system introduced. |
| 2008 |
First audit for GLP compliances for medical devices (latest audit: 2015). |
| 2009 |
X-ray apparatuses introduced to Hashima Laboratory and Shuzenji Branch. |
| 2011 |
Kisosansen Branch (BSL-2) specialized for infection studies established, and commenced infection studies. |
| Certification of animal studies by Japan Health Sciences Foundation acquired. |
| 2012 |
New facilities specialized for minipigs established at Hashima Laboratory. |
| 2013 |
Facilities for minipigs at Shuzenji Branch enlarged. |
| 2015 |
First audit for GLP compliances for regenerative medical products. |
| 2017 |
Facilities for minipigs at Shuzenji Branch further enlarged. |
| New facilities dedicated to immunodeficient animals established at Hashima Laboratory. |
| 2020 |
Awarded full accreditation by AAALAC International (Shuzenji Branch). |
